Liver Transplantation for perihiliar cholangiocarcinoma: do we need to move forward?

In this episode, Dr Taizo Hibi and Dr Cristina Dopazo discuss a recent review article in Hepatoma Research titled: “Liver Transplantation for perihiliar cholangiocarcinoma: Do we need to move forward?". They discuss the outstanding results of the Mayo Clinic protocol based on liver transplantation after neoadjuvant chemoradiation in very selected patients with unresectable de novo pCCA or resectable pCCA arising under primary sclerosing cholangitis. However, its application is diverse worldwide. They also discuss the recommended tools for diagnostic work-up, the need for updating the systemic therapy following the results of the latest clinical trials, the role of cfDNA, and the importance of multicenter collaborations.