#075: Todd Spear & Katie Emerson: Nutrition21 at SupplySide West 2022

https://blog.priceplow.com/pod....cast/todd-spear-kati In early November of 2022, the SupplySide West convention was held at Mandalay Bay in Las Vegas, showcasing the premiere ingredients and technology in the dietary supplement and functional food industries. Todd Spear and Katie Emerson of Nutrition21 join the PricePlow Podcast at SupplySide West 2022 to talk research, trends, nitric oxide supplements, and more! As is tradition, Team PricePlow met with Team Nutrition21 to catch up in-person -- Nutriton21 being the industry-leading developer and supplier of dietary supplement ingredients well-known for ingredients such as Nitrosigine, nooLVL, Chromax, and Velositol. Mike and Ben met with Todd Spear (Sports Nutrition Category Leader) and Katie Emerson (Manager of Scientific Affairs) to discuss the latest research and industry trends coming out of both the industry at large and Nutrition21's team. This was a fun, informative, and fast-paced conversation where you get to meet some of the personalities behind the brands. We cover all four of Nutrition21's ingredients listed above, discuss their research, potential opportunities, and the reasons these ingredients are important in today's dietary landscape. You can watch on YouTube below, or listen on your favorite podcast app in our audio feeds: https://www.youtube.com/watch?v=jGFGz5aCUMM Audio Version: Subscribe to the PricePlow Podcast on Your Favorite Service iTunesSpotify Google Podcasts 0:00 - Opening Mike and Katie are drinking nooLVL and Ben's drinking Nitrosigine. Mike briefly mentions that Todd was on the podcast long ago -- flashback to #017: What is Velositol? -- and Ben recalls the two previous SSW interviews, 2019 with David Sandler and #055: Sarah Perez Ojalvo. 2:00 - Nitrosigine Not only does Nitrosigine immediately boost N.O. levels, it keeps them elevated for a period of up to 2 weeks! Ben asks Todd and Katie to explain the beginnings of Nitrosigine, Nutrition21's patented[1] nitric oxide boosting ingredient that's scientifically known as inositol-stabilized arginine silicate. They received an official NDI (New Dietary Ingredient) with the FDA in 2013,[2] and have been selling it ever since. 3:15 - Nitrosigine and Cognitive Function We begin talking about the enhancement of cognitive flexibility that Nitrosigine can support,[3-7] especially when athletes become exhausted.[6,7] This makes sense because blood flows to the brain (not just the muscles) and the inositol component can support neurotransmitters as well. 3:45 - nooLVL vs. Nitrosigine A nitric oxide booster that improves cognition?! Yes - Nutrition21 passed around this helpful infographic after the Nitrosigine cognition study on healthy young adults was published.[5] The above Nitrosigine research led to the creation of nooLVL, a nitric oxide boosting nootropic ingredient that is also based upon inositol-stabilized arginine silicate, but is studied in gamers.[8-10] nooLVL has more inositol than Nitrosigine, and Katie mentions a new abstract published that explains why they went with the inositol dose they did.[11] 5:30 - What is inositol? We then get into the specifics of inositol, which is interesting because there's no conclusive definition for what exactly it is and primarily does. Todd explains some of the detailed chemistry behind its original inclusion in Nitrosigine -- before the cognitive component was even explored -- and much of it comes down to its ability to stabilize the molecule and enable better silica and arginine ratios. 7:00 - The problems with traditional L-arginine Mike explains that L-arginine requires huge doses to get clinically significant results, but such doses have been shown in numerous studies to lead to major GI issues.[12] Nitrosigine, dosed at 1.5 grams, allows for far smaller dosing. 8:30 - The big scoop craze