PODCAST: Organophosphate Poisoning

Introduction Used as pesticides Used as weapons (nerve agents) Sarin Gas, VX Gas, Novichok Transdermal, Inhalation, Ingestion Clinical Presentation Muscarinic Activation (Dumbels Mnemonic) Defication Urination Myosis Bradycardia, Bronchospasm, and Bronchorrhea “The Killer B’s” Emesis Lacrimation Salivation and Sweating Nicotinic Activation Muscle weakness and paralysis CNS Activation Respiratory Depression Altered Mental Status Seizures Treatment Atropine Reverses Dumbels Keep giving and doubling the dose until brochorrhea and bradycardia resolve Pralidoxime Only works before ‘aging’ occurs Diazepam Stops the seizures The post PODCAST: Organophosphate Poisoning first appeared on האיגוד הישראלי לרפואה דחופה.