Sarah Best and Saskia Freytag - Dissecting high-grade glioma spatially

Sarah Best and Saskia Freytag are laboratory heads at the Brain Cancer Research Lab in Australia's Walter and Eliza Hall Institute of Medical Research.In this podcast episode, they share their views and interest for tackling high-grade glioma by dissecting its heterogeneity and its interactions with the microenvironment. They also discuss why Spatial Biology was key to uncover subtype-specific heterogeneity and how they combined the power of GeoMx DSP and CosMx SMI to maximize their understanding of this cancer type. At the end of the episode, they comment on the future of spatial multiomics, why location matters and how it is revolutionizing the field.